CALERA Research
Core Body Temperature for Research
CALERA® Research is revolutionizing how Core Body Temperature is monitored. Presenting a breakthrough in non-invasive, accurate, and continuous data collection.
Why monitor core body temperature for your research applications?
Core Body Temperature is a vital parameter for monitoring an individual’s health status and refers to the body’s organs’ temperature. It fluctuates following physiological processes, such as physical activity, circadian and ovulation rhythm, or various illnesses and sleeping disorders.
Before CALERA®, it was only possible to accurately monitor the core temperature in study participants using invasive methods such as uncomfortable rectal thermometers or expensive ingestible pills. The non-invasive CALERAresearch makes monitoring of the core temperature straightforward and manageable.
Other devices on the market try to estimate core body temperature via skin surface temperature. Due to the complexity of thermal regulation and the thermal influences from changing environmental conditions and physical activity, this estimate does not come close to CALERA®’s accuracy and reliability.
What about in-ear (tympanic) and oral thermometers? These methods can provide accurate results during stable conditions like in a hospital bed. But these single-point measurements do not provide much information. The continuous temperature signal of CALERA will give much better insights.
Accurate Research Data with our Heatflux Monitoring Solution
Our solution combines Heatflux as the primary component for non-invasive core body temperature tracking, a skin temperature sensor, algorithm integration for your microcontroller, and our expertise in integration.
Our algorithms for Core Body Temperature monitoring are developed and validated in collaboration with renowned researchers and hospitals.
Heat flux definition & working principle It describes the rate of heat energy that passes through a surface. Depending on its exact definition, its unit can be expressed as either W/m2 or W. Practically, it originates from temperature differences in a given system. The induced heat always flows from the hot to the cold side. In order for this phenomenon to exist, it requires, not only a temperature difference but also a medium through which it can flow.
This phenomenon is complex and multidimensional and implies the combination of three distinctive mechanisms based on the medium or the set of media where the temperature gradient occurs. Indeed, heat can flow through solid materials (in which case it is called conduction), through gases and liquids (which is called convection), and through electromagnetic waves (which is called radiation).
In addition, heat flux depends on the temperature difference and the thermal transfer coefficient. The following equation defines heat flux with respect to the temperature difference and the thermal transfer coefficient: **HF = ∆T x HTC **with HF, the Heat Flux, in W/m2, ∆T, the temperature difference [K], and HTC, the heat transfer coefficient, in W/(m2K).
Research Focus
Join us at CALERAresearch and discover how our innovative technology can revolutionize your research. Experience the ease, accuracy, and reliability of CALERA® as you uncover valuable data about core body temperature and its impact on human health. A continuous core body temperature signal has countless applications, and we are working together with many partners and researchers in various fields: Physiology, Sports, Fever & Sepsis detection, Ovarian Cycle, Thermal Comfort, Circadian Cycle, Sleep Disorders, Neurological diseases.
CALERA research received the Emergency Use Authorization in the US, making it available for clinical use during the Covid-19 crisis. We are currently filing for full FDA approval.
Curious to know more about CALERA® Research?
Visit our product page to explore its features and read the latest publications using our technology.
FAQs
CORE vs CALERA®
Q: What separates CORE and CALERA® devices?
A: The CORE devices target sports applications, sharing the same casing but offering fewer features compared to CALERA® devices. CALERA®research offers convenient multiple devices management, 1-second data resolution via an exclusive PC tool, individual calibration for reliability, research support, algorithm choice based on activity, and the option to rerun raw data on future algorithms. Heatflux data is also available with a license.
Warranty
Q: What's the warranty policy?
A: We ensure product functionality by calibrating each unit before shipping. We guarantee replacement for any malfunctions caused by us.
Disposable?
Q: Are CALERA® research devices disposable?
A: No, CALERA® research integrates the sensor, making disposability a non-issue. You can use the same device for years, only replacing the disposable patches used for adherence.
Heart Rate Compatibility
Q: Which heart rate monitors work with the device?
A: The device can be connected with multiple heart rate monitors; you can check them here.
Every heart rate monitor which has ANT+ connectivity can be paired with CALERA® research.
Bluetooth Range
Q: How far does Bluetooth reach?
A: Bluetooth's limited range matters only during initial device connection. Once in logging mode, distance isn't a concern. Data is stored and later downloaded from the research tool.
Number of Connected Devices
Q: How many CALERA® research devices can be connected to the program?
A: There is no upper limit, with some researchers successfully using over 100 devices.
Calibration Time
Q: How long does device calibration take?
A: The device provides accurate measurements in about 15 minutes.
Product Versatility
Q: Is your product solely for sports?
A: No, our product serves multiple uses, including circadian rhythm, women's health, work safety, animal monitoring, and patient care.
Temperature Range
Q: What's the device's temperature tolerance?
A: It performs well even in high temperatures. Accuracy may drop below 36°C and above 42°C.
Measurement Interval
Q: What's CALERA® 's measurement interval?
A: CALERA® delivers data at one-second intervals in logging mode.